Developmental aspects of splenic function in sickle cell diseases

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Developmental aspects of splenic function in sickle cell diseases.

In order to study developmental aspects of splenic function and dysfunction in children with Hb SS disease and other Hb S syndromes. red cells were examined by interference phase-contrast microscopy. In the youngest children studied (<1 yr) the number of red blood cells bearing ‘pocks” was low (<1 %), the same as in normal eusplenic controls. In most children over 8 yr of age. >12 % of the red ...

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BACKGROUND We tried to understand whether or not there are lowered prevalences of terminal consequences of sickle cell diseases (SCDs) with tonsilectomy. METHODS All cases with SCDs were taken into the study. RESULTS The study included 334 patients (164 females). There were 27 cases with tonsilectomy and 307 cases without. The mean ages, female ratios, and prevalences of associated thalasse...

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ژورنال

عنوان ژورنال: Blood

سال: 1979

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v53.3.358.358